Purified Anti-Human CD49f Antibody[GoH3] (AN008930P)
| Alternate Names | ITA, ITGA, Integrin alpha, Processed integrin alpha, alpha, VLA, CD49f, ITGA6B, VLA-6, Integrin alpha 6, ITGA6, alpha 6, Alpha6p, CD49 antigen-like family member F, Integrin, Integrin alpha6B, ITA6, Processed integrin alpha-6, VLA 6, &, alpha-6 integrin-n, VLA-6&, alpha |
| Clone | |
| Verified Samples | Verified Samples in FCM: Human peripheral blood platelet cell |
| Dilution | FCM 2 μg/mL(0.5×106-1×106 cells) |
| Background | CD49f is a 120 kD integrin family member also known as VLA-6 α chain and α6 integrin subunit. CD49f associates with either integrin β1 (CD29) or integrin β4 (CD104) to form receptors (VLA-6 or α6β4 complex) for laminin and kalinin. CD49f is expressed on platelets, monocytes, T cells, placental trophoblasts, and epithelial and endothelial cells. CD49f is involved in adhesion and can act as a co-stimulatory molecule for T cell activation and proliferation. |
| Immunogen | Recombinant Human CD49f protein |
| Abbre | CD49f |
| Swissprot | |
| Host | Rat |
| Reactivity | Human |
| Clonality | Monoclonal |
| Purification Method | >98%, Protein A/G purified |
| Isotype | Rat IgG2a, κ |
| Isotype Control | Purified Rat IgG2a, κ Isotype Control[2A3] |
| Applications |
FCM
|
| Research Areas | Stem Cells;Signal Transduction;Developmental Biology;G protein signaling;PI3K-Akt Signaling Pathway;MAPK-Erk Signaling Pathway;Cytoskeleton;CDs;Embryonic Stem Cells;Hematopoietic Stem Cell Markers |
| Cellular Localization |
Cell membrane
|
| Concentration |
≥ 1 mg/mL
|
| Conjugation | Unconjugated |
| Storage Buffer | Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling. |
| Storage | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. |
| Expiration Date | 12 months |
| Shipping | Ice bag |
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